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Source Naturals SAMe (s-adenosyl-l-methionine) 200mg, 20 Tablets New Sealed Box. Source Naturals SAMe is a stable, bioavailable form of S-adenosyl-L-methionine. These tablets are enteric coated and blister packed to prevent breakdown and inactivation of the ingredients. SAMe is present in every living cell in the body and plays an important part in many critical cellular functions Suggested Use: 2 tablets, 1 to 3 times daily. Take tablets on an empty stomach.